PAK2 Polyclonal Antibody

Uniprot : Q13177
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14278

      Synonyms:C-t-PAK2,CB422,EC 2.7.11.1,Gamma PAK,Gamma-PAK,hPAK65,Kinase,p21 (CDKN1A) activated kinase 2,p21 (CDKN1A)-activated kinase 2a,p21 activated kinase 2,p21 protein (Cdc42/Rac)-activated kinase 2,p21 protein Cdc42 Rac activated kinase 2,p21-activated kinase 2,p21-activated kinase,65-KD,p21-activated protein kinase I,p21CDKN1A activated kinase 2,p27,p34,p58,p65PAK,PAK 2,PAK-2,PAK-2p34,Pak2,PAK2,PAK65,PAKgamma,S6 H4 kinase,S6/H4 kinase,Serine threonine protein kinase PAK 2,Serine/threonine protein kinase PAK 2

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms C-t-PAK2,CB422,EC 2.7.11.1,Gamma PAK,Gamma-PAK,hPAK65,Kinase,p21 (CDKN1A) activated kinase 2,p21 (CDKN1A)-activated kinase 2a,p21 activated kinase 2,p21 protein (Cdc42/Rac)-activated kinase 2,p21 protein Cdc42 Rac activated kinase 2,p21-activated kinase 2,p21-activated kinase,65-KD,p21-activated protein kinase I,p21CDKN1A activated kinase 2,p27,p34,p58,p65PAK,PAK 2,PAK-2,PAK-2p34,Pak2,PAK2,PAK65,PAKgamma,S6 H4 kinase,S6/H4 kinase,Serine threonine protein kinase PAK 2,Serine/threonine protein kinase PAK 2
      Swissprot Q13177
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human PAK2
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:200-1:1000, IHC 1:50-1:200
      Concentration 0.5 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm and Nucleus. Cytoplasm>perinuclear region. Membrane. Interaction with ARHGAP10 probably changes PAK-2p34 location to cytoplasmic perinuclear region. Myristoylation changes PAK-2p34 location to the membrane.
      Tissue specificity Ubiquitously expressed. Higher levels seen in skeletal muscle, ovary, thymus and spleen.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. 

      Images

      Western Blot analysis of A172 cell using PAK2 Polyclonal Antibody at dilution of 1:400

      Immunohistochemistry of paraffin-embedded Human liver cancer using PAK2 Polyclonal Antibody at dilution of 1:40

      Immunohistochemistry of paraffin-embedded Human thyroid cancer using PAK2 Polyclonal Antibody at dilution of 1:40

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