PARP3 Polyclonal Antibody (E-AB-11473)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human thyroid cancer, Human liver cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human PARP3 |
| Abbre | PARP3 |
| Synonyms | ADP ribosyltransferase (NAD+, ADP ribosyltransferase diphtheria toxin like 3, ADPRT-3, ADPRT3, ADPRTL2, ADPRTL3, ARTD3, IRT 1, IRT1, NAD(+) ADP ribosyltransferase 3, NAD(+) ADP-ribosyltransferase 3, NAD+ ADP ribosyltransferas, hPARP 3, hPARP-3, hPARP3, poly (ADP ribose) |
| Swissprot | |
| Cellular Localization | Nucleus. Cytoplasm>cytoskeleton>centrosome. Cytoplasm>cytoskeleton>centrosome>centriole. Core component of the centrosome. Preferentially localized to the daughter centriole throughout the cell cycle. According to PubMed:16924674, it is almost exclusively localized in the nucleus and appears in numerous small foci and a small number of larger foci whereas a centrosomal location has not been detected. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Other Clones
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Other Formats
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Unconjugated
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