PerCP/Cyanine5.5 Anti-Human CD163 Antibody[GHI/61] (E-AB-F1298J)
![PerCP/Cyanine5.5 Anti-Human CD163 Antibody[GHI/61] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
Conjugation: PerCP/Cyanine 5.5
Elab Fluor®700 PerCP/Cyanine 5.5 Unconjugated Show More
| Isotype | Mouse IgG1, κ |
| Host | Mouse |
| Reactivity | Human |
| Applications | FCM |
| Clonality | Monoclonal |
| Abbre | CD163 |
| Synonyms | ED2(rat)Hemoglobin/Haptoglobin Complex ReceptorM130RM3/1macrophage-associated antigenp155, GHI/61 |
| Swissprot | |
| Cellular Localization | Membrane;Secreted |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Cell Biology, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers |
| Clone No. | GHI/61 |
| Conjugation | PerCP/Cyanine 5.5 |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
| background | CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases. |
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