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Recombinant 2019-nCoV 3C-like Proteinase Protein (His Tag)

Uniprot : YP_009725301.1

Cat.No.:PKSR030465
Expression host: E.coli

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Description

Synonyms	M Proteinase; 3CL Proteinase
Species	SARS-CoV-2
Expression_host	E.coli
Sequence	Ser1-Gln306
Accession	YP_009725301.1
Mol_Mass	36.1 kDa
AP_Mol_Mass	33 kDa
Tag	N-6His
Bio_Activity	Testing in progress

Properties

Purity	>95 % as determined by reducing SDS-PAGE.
Endotoxin level	<1.0 EU per µg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, 1 mM EDTA, 10% Glycerol, pH 7.4.
Reconstitution	Not Applicable

Background

The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents.

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