Click here to view cell apoptosis assay products
×

Recombinant 2019-nCoV Methyltransferase / ME Protein (His Tag)

Uniprot : YP_009724390.1
  • Cat.No.:PKSR030513

  • Expression host: E. coli

To Purchase PKSR030513

Size:
  • 100µg
Price: $1105
Qty:

Description

Synonyms Methyltransferase, ME
Species virus
Expression_host E. coli
Sequence Ser6799-Asn7096
Accession YP_009724390.1
Mol_Mass 33.46 kDa.
Tag C-His

Properties

Purity > 85 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per µg as determined by the LAL method.
Storage Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from sterile 20 mM Tris 150 mM NaCl, pH 8.3.
Reconstitution Please refer to the printed manual for detailed information.

Background

Coronavirus encodes the 2'-O-MTase(2'O Methyltransferase) that is composed of the catalytic subunit nsp16 and the stimulatory subunit nsp10 and plays an important role in virus genome replication and evasion from innate immunity during viral infection. Nonstructural protein 16 (NSP16) / viral 2'O-methyltransferase (2'O-MTase) is highly conserved. The conserved 2'O-MTase activity is important for CoV pathogenesis and NSP16 is a conserved universal target for rapid live attenuated vaccine design in an expanding Coronavirus outbreak setting, such as COVID-19. Targeting on the 2'O-methylation pathway on SARS-CoV replication and pathogenesis can be the treatment options for vaccine and anti-viral durgs development which can against SARS-CoV-2,SARS-CoV, MERS-CoV or other RNA and DNA viruses.

Citations

From now on, if you have published a paper by using any of our products since 1/1/2019, fill out the “Elabscience Publication Reward Application Form”carefully and send it to orders@elabscience.com, we will get back to you with the reward after we confirm it ASAP!

View more details about our Publication Reward >>

Reviews/Q&A

  • Show all
  • Reviews
  • Q&A
... Show All Show Less

People Also Bought

Apply for
*Product Name:
*Catalog Number:
*Name:
*Email:
*Message:
*Country:
*When will you use it?

*Captcha: