Recombinant BLyS/TNFSF13B/BAFF Monoclonal Antibody (AN300173P)

Name: Recombinant BLyS/TNFSF13B/BAFF Monoclonal Antibody
Brand: Elabscience
SKU: AN300173P
Price: 380.0 USD
Availability: InStock

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Recombinant BLyS/TNFSF13B/BAFF Monoclonal Antibody - 1

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Verified Samples	Verified Samples in WB:U937
Dilution	WB: 1:1000；ICC/IF: 1:100；FC: 1:200-1:500；IP: 1:20-1:50
Isotype	IgG
Host	Rabbit
Reactivity	Human
Applications	WB, ICC/IF, FC, IP
Clonality	Recombinant;Monoclonal
Immunogen	Recombinant Human BLyS / TNFSF13B / BAFF protein
Abbre	TNFSF13B
Synonyms	UNQ, PRO, ZTNF, TNF- and APOL-related leukocyte expressed ligand, TNFSF, TNFSF13B, BAFF, BLYS, CD257, DTL, TALL-1, TALL1, THANK, TNFSF20, TNLG7A, ZTNF4, Tumor necrosis factor ligand superfamily member 13B, B lymphocyte stimulator, B-cell-activating factor, Dendritic cell-derived TNF-like molecule, TNF- and APOL-related leukocyte expressed ligand 1, UNQ401, PRO738, BAFF, TNFSF13b, TALL-1, ApoL related ligand TALL 1, B cell Activating Factor, CD 257, CD257 antigen, Delta BAFF, Dendritic cell derived TNF like molecule, DTL precursor, soluble form, TALL 1, TN13B, TNF and APOL related leukocyte expressed ligand 1, TNF homolog that activates apoptosis, TNF homolog that activates apoptosis NKFB and JNK., Tumor necrosis factor (ligand) superfamily member 13b, Tumor necrosis factor ligand 7A, Tumor necrosis factor ligand superfamily member 20, Tumor necrosis factor like protein ZTNF4, Tumor necrosis factor superfamily member 13B
Swissprot	Q9Y275
Calculated MW	31 kDa
Observed MW	31 kDa Western blotting is a method for detecting a certain protein in a complex sample based on the specific binding of antigen and antibody. Different proteins can be divided into bands based on different mobility rates. The mobility is affected by many factors, which may cause the observed band size to be inconsistent with the expected size. The common factors include: 1. Post-translational modifications: For example, modifications such as glycosylation, phosphorylation, methylation, and acetylation will increase the molecular weight of the protein. 2. Splicing variants: Different expression patterns of various mRNA splicing bodies may produce proteins of different sizes. 3. Post-translational cleavage: Many proteins are first synthesized into precursor proteins and then cleaved to form active forms, such as COL1A1. 4. Relative charge: the composition of amino acids (the proportion of charged amino acids and uncharged amino acids). 5. Formation of multimers: For example, in protein dimer, strong interactions between proteins can cause the bands to be larger. However, the use of reducing conditions can usually avoid the formation of multimers. If a protein in a sample has different modified forms at the same time, multiple bands may be detected on the membrane.
Cellular Localization	Cell membrane, Secreted.
Tissue Specificity	Peripheral blood Leukocytes, Spleen, Lymph node, Bone marrow.
Concentration	1 mg/mL
Buffer	0.2 μm filtered solution in PBS
Purification Method	Protein A
Research Areas	Cell Biology, Immunology, Cancer
Clone	A1287
Conjugation	Unconjugated
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping	Ice bag
background	The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]