Recombinant Cynomolgus CTLA-4/CD152 Protein (Fc Tag)

    • Recombinant Cynomolgus CTLA-4 / CD152 Protein (C-Fc)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Cynomolgus CTLA-4 / CD152 Protein (C-Fc)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Cynomolgus CTLA-4 / CD152 Protein (C-Fc)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSQ050042

      Synonyms:Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; CTLA-4; CD152; CTLA4

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $62

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      Overview

      Synonyms Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; CTLA-4; CD152; CTLA4
      Species Cynomolgus
      Expression_host Human Cells
      Sequence Ala37-Ser160
      Accession G7PL88
      Mol_Mass 40.2 kDa
      AP_Mol_Mass 45-60 kDa
      Tag C-Fc

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 100 mM Glycine, pH 7.5.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4.

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      MSDS for ELISA ISO 9001

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