Recombinant Cynomolgus SIGLEC5/CD170 Protein (His Tag)

    • Recombinant Cynomolgus SIGLEC5 / CD170 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Cynomolgus SIGLEC5 / CD170 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Cynomolgus SIGLEC5 / CD170 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSQ050010

      Synonyms:Sialic acid-binding Ig-like lectin 5; Siglec-5; CD170;CD33L2;OB-BP2;OBBP;OBBP2;SIGLEC-5;SIGLEC5

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $178

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      Overview

      Synonyms Sialic acid-binding Ig-like lectin 5; Siglec-5; CD170;CD33L2;OB-BP2;OBBP;OBBP2;SIGLEC-5;SIGLEC5
      Species Cynomolgus
      Expression_host Human Cells
      Sequence Glu17-Gly435
      Accession A0A0B4J1D1
      Mol_Mass 46.8 kDa
      AP_Mol_Mass 90 kDa
      Tag C-His

      Properties

      Purity > 90% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH8.0.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Sialic acid-binding Ig-like lectin 5 is a protein that in Cynomolgus is encoded by the SIGLEC5 gene, Cynomolgus SIGLEC5 cDNA encodes 551 amino acids (aa) that include a 16 aa signal sequence, a 439aa extracellular domain (ECD) with three Ig-like domains, a transmembrane region and a cytoplasma tail. No Siglec has been shown to recognized any cell surface ligand other than sialic acids, suggesting that interactions with glycans containing this carbohydrate are important in mediating the biological functions of Siglecs. Siglec5 to 11 share a high degree of sequence similarity with CD33/Siglec3 both in their extracellular and intracellular regions. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

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      MSDS for ELISA ISO 9001

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