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Recombinant Human Apolipoprotein H/ApoH Protein (His Tag)

Uniprot : P02749

Cat.No.:PKSH032087
Expression host: HEK293 Cells

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Description

Synonyms	Beta-2-Glycoprotein 1;APC inhibitor;Activated Protein C-Binding Protein;Anticardiolipin Cofactor;Apolipoprotein H;Apo-H;Beta-2-Glycoprotein I;B2GPIBeta(2)GPI;APOH;B2G1;B2GP1;BG
Species	Human
Expression_host	HEK293 Cells
Sequence	Gly20-Ser345
Accession	P02749
Mol_Mass	37.3 kDa
AP_Mol_Mass	45-70 kDa
Tag	C-His
Bio_Activity	Not validated for activity

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background

Apolipoprotein H (ApoH) is a 50 kDa variably glycosylated member of the complement control superfamily of proteins. Human ApoH is a major phospholipid binding protein and an important component to measure in the assessment of anti-phospholipid syndrome. Hepatocyte-derived ApoH binds to negatively charged phospholipids . It circulates as a component of lipoprotein particles and as a lipid-free serum protein. Human ApoH is also more specific than anti-cardiolipin antibodies and its presence correlates better with thrombotic risk. Mature human ApoH shares 76% and 82% aa sequence identity with mouse and rat ApoH.

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