Recombinant Human BTN3A1/CD277 Protein (Fc Tag)

    • Recombinant Human BTN3A1 / CD277 Protein (C-Fc)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human BTN3A1 / CD277 Protein (C-Fc)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human BTN3A1 / CD277 Protein (C-Fc)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033744

      Synonyms:Butyrophilin subfamily 3 member A1; CD277; BTN3A1; BTF5

      Size:
      • 10μg
      • 50μg
      Qty:
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      Price: $92

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      Overview

      Synonyms Butyrophilin subfamily 3 member A1; CD277; BTN3A1; BTF5
      Species Human
      Expression_host Human Cells
      Sequence Gln30-Gly254
      Accession O00481
      Mol_Mass 50.8 kDa
      AP_Mol_Mass 55 kDa
      Tag C-Fc

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Butyrophilin Subfamily 3 Member A1 (BTN3A1/CD277) is a type I transmembrane glycoprotein member of the Ig superfamily. It is expressed on a wide variety of immune cells. Similar to BTN3A2 and BTN3A3, BTN3A1 is composed of an extracellular N-terminal IgV and a membraneproximal IgC domain followed by a transmembrane domain and a cytoplasmic tail. These Ig domains are also found in B7 family costimulatory molecules, suggesting structural and functional similarities between the two protein families. BTN3A1 acts as a critical protein for the activation of Vγ9Vδ2 T cells following detection of distressed cells. The anti-tumor responses of Vγ9Vδ2 T cells may be enhanced with agonistic anti-BTNA3 antibodies.

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      MSDS for ELISA ISO 9001

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