Recombinant Human CD3 epsilon/CD3E (C-Fc-Avi) Biotinylated
Price: $ 924
Price: $ 342
Size:
100μg
20μg
Quantity:
- Expression Host: HEK293 Cells
- Accession: P07766
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Product Details
Synonyms | T-Cell Surface Glycoprotein CD3 Epsilon Chain;T-Cell Surface Antigen T3/Leu-4 Epsilon Chain;CD3e;CD3E;T3E |
Species | Human |
Expression Host | HEK293 Cells |
Sequence | Asp23-Asp126 |
Accession | P07766 |
Calculated Molecular Weight | 40.5 kDa |
Observed Molecular Weight | 45-60 kDa |
Tag | C-Fc-Avi |
Purity | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Reconstitution | Please refer to the printed manual for detailed information. |
Background | T-Cell Surface Glycoprotein CD3 ε Chain (CD3ε) is a single-pass type I membrane protein. CD3ε contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3ε is a polypeptide encoded by the CD3E gene on chromosome 11 in humans. The T cell receptor-CD3 complex (TCR/CD3 complex) is involved in T-cell development and several intracellular signal-transduction pathways. This complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. The T cell receptor-CD3 complex is unique in having ten cytoplasmic immunoreceptor tyrosine-based activation motifs (ITAMs). TCR/CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. |
Modification | Biotinylated |