Recombinant Human CD47/IAP Protein (His Tag)(Active)

    • Recombinant Human CD47 / IAP Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human CD47 / IAP Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human CD47 / IAP Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033600

      Synonyms:Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; Integrin-Associated Protein; IAP; Protein MER6; CD47; MER6

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $98

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      Overview

      Synonyms Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; Integrin-Associated Protein; IAP; Protein MER6; CD47; MER6
      Species Human
      Expression_host Human Cells
      Sequence Gln19-Pro139
      Accession Q08722
      Application Functional ELISA
      Mol_Mass 14.76 kDa
      AP_Mol_Mass 34 kDa
      Tag C-His
      Bio_Activity Immobilized Human SIRPA-Fc(Cat: PKSH033061) at 10μg/ml(100 μl/well) can bind Human CD47-His. The ED50 of Human CD47-His is 4.18 ng/ml .

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of 10mM Tris-Citrate, 150mM NaCl, pH 8.0.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      CD47(Integrin-Associated Protein,IAP) is a 40 - 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes.

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      MSDS for ELISA ISO 9001

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