Recombinant Human CD4/LEU3 Protein (His Tag)

    • Recombinant Human CD4 / LEU3 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human CD4 / LEU3 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human CD4 / LEU3 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033506

      Synonyms:T-cell surface glycoprotein CD4;T-cell surface antigen T4/Leu-3;CD4;Scd4;CD4mut

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $92

      Lead Time: Order now, ship in 3 daysWelcome to order from local distributors.

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      Overview

      Synonyms T-cell surface glycoprotein CD4;T-cell surface antigen T4/Leu-3;CD4;Scd4;CD4mut
      Species Human
      Expression_host Human Cells
      Sequence Lys26-Trp390
      Accession P01730
      Mol_Mass 41.7 kDa
      AP_Mol_Mass 58 kDa
      Tag C-His

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      CD4 is an approximately 55 kDa type I transmembrane glycoprotein that is expressed predominantly on thymocytes and a subset of mature T lymphocytes. It is a standard phenotype marker for the identification of T cell populations. Mature human CD4 consists of a 371 amino acid extracellular region containing four immunoglobulin-like domains, a 22 aa transmembrane segment, and a 40 aa cytoplasmic domain. CD4 is expressed along with CD8 on double positive T cells during their development in the thymus. CD4 binds directly to MHC class II molecules on antigen presenting cells (10). This interaction contributes to the formation of the immunological synapse which is focused around the TCR-MHC class II-antigenic peptide interaction. CD4 also functions as a chemotactic receptor for IL-16 and, in human, as a co-receptor for the gp120 surface glycoprotein of HIV-1.

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      MSDS for ELISA ISO 9001

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