Recombinant Human CTLA4 Protein (Fc & Avi Tag)(Active)

    • Recombinant Human CTLA4 / CD152 Protein (C-Fc-Avi)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human CTLA4 / CD152 Protein (C-Fc-Avi)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human CTLA4 / CD152 Protein (C-Fc-Avi)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033803

      Synonyms:Cytotoxic T-lymphocyte protein 4;Cytotoxic T-lymphocyte-associated antigen 4;CTLA4;CD152;Cytotoxic T-Lymphocyte-Associated Protein 4

      Size:
      • 20μg
      • 100μg
      Qty:
      - +
      Price: $342

      Lead Time: Order now, ship in 3 daysWelcome to order from local distributors.

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      Overview

      Synonyms Cytotoxic T-lymphocyte protein 4;Cytotoxic T-lymphocyte-associated antigen 4;CTLA4;CD152;Cytotoxic T-Lymphocyte-Associated Protein 4
      Species Human
      Expression_host Human Cells
      Sequence Lys36-Asp161
      Accession P16410
      Application Functional ELISA
      Mol_Mass 41.5 kDa
      AP_Mol_Mass 57-60 kDa
      Tag C-Fc-Avi
      Bio_Activity Immobilized Human CTLA-4-Fc-Avi at 2μg/ml(100 μl/well) can bind Human B7-2-6His(Cat: PKSH033722). The ED50 of Human CTLA-4-Fc-Avi is 1.98 ug/mL

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Cytotoxic T-lymphocyte protein 4, is a single-pass type I membrane protein. It is widely expressed with highest levels in lymphoid tissues. CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4.

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      MSDS for ELISA ISO 9001

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