Recombinant Human EphA7/EHK3 Protein (His Tag)(Active)

    • Recombinant Human EphA7 / EHK3 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human EphA7 / EHK3 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human EphA7 / EHK3 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033689

      Synonyms:Ephrin Type-A Receptor 7; EPH Homology Kinase 3; EHK-3; EPH-Like Kinase 11; EK11; hEK11; EPHA7; EHK3; HEK11

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $111

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      Overview

      Synonyms Ephrin Type-A Receptor 7; EPH Homology Kinase 3; EHK-3; EPH-Like Kinase 11; EK11; hEK11; EPHA7; EHK3; HEK11
      Species Human
      Expression_host Human Cells
      Sequence Gln28-Ile556
      Accession Q15375
      Application Functional ELISA
      Mol_Mass 60.19 kDa
      AP_Mol_Mass 72 kDa
      Tag C-His
      Bio_Activity Immobilized Human EphA7-His at 2μg/ml(100 μl/well) can bind Human EFNA4-Fc-6His(Cat: PKSH032392). The ED50 of Human EphA7-His is 1.5190 ug/ml .

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Ephrin Type-A Receptor 7 (EPHA7) is a single-pass type I membrane protein which belongs to the Eph family of transmembrane receptor tyrosine kinases. It contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile alpha motif) domain. EPHA7 is a receptor for members of the ephrin-A family. Eph receptors are largely expressed throughout the ectoderm, mesoderm, and endoderm of vertebrate embryos. EPHA7 functions as a repulsive guidance molecule during the targeting of retinal axons to the superior colliculus and of neocortical axons to the thalamus. EPHA7 is expressed at a substantial level in most human lung cancers. The high expression of EPHA7 protein may participate in the malignancy transformation, invasion progression and metastasis of primary hepatocellular carcinoma. EPHA7 may involve in smoking related lung carcinogenesis.

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      MSDS for ELISA ISO 9001

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