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Recombinant Human FKBP3/FKBP25 Protein (His Tag)

Uniprot : Q00688
  • Cat.No.:PKSH032876

  • Expression host: E.coli

To Purchase PKSH032876

  • 10μg
  • 50μg
Price: $209


Synonyms Peptidyl-prolyl cis-trans isomerase FKBP3;PPIase FKBP3;25 kDa FK506-binding protein;25 kDa FKBP;FKBP-25;FK506-binding protein 3;FKBP-3;Immunophilin FKBP25;Rapamycin-selective 25 kDa immunophilin;Rotamase;FKBP25
Species Human
Expression_host E.coli
Sequence Met 1-Asp224
Accession Q00688
Mol_Mass 27.3 kDa
AP_Mol_Mass 30 kDa
Tag N-His


Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 1mM DTT, 10% Glycerol, pH 8.0.
Reconstitution Not Applicable


FKBP25 contains 1 PPIase FKBP-type domain; belongs to the FKBP-type PPIase family. FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin; as well as histone deacetylases; the transcription factor YY1; casein kinase II; and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.



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