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Recombinant Human GPD1/GDP-C Protein (Human Cells, His Tag)

Uniprot : P21695

Cat.No.:PKSH032505
Expression host: HEK293 Cells

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Description

Synonyms	Glycerol-3-Phosphate Dehydrogenase [NAD(+)] Cytoplasmic;GPD-C;GPDH-C;GPD1;HTGTI
Species	Human
Expression_host	HEK293 Cells
Sequence	Met 1-Met349
Accession	P21695
Mol_Mass	38.6 kDa
AP_Mol_Mass	32-48 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Glycerol, pH 8.0.
Reconstitution	Not Applicable

Background

Glycerol-3-Phosphate Dehydrogenase [NAD(+)]; Cytoplasmic (GPDH-C) belongs to the NAD-Dependent Glycerol-3-Phosphate Dehydrogenase family. GPDH-C plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of Dihydroxyacetone Phosphate (DHAP) and reducing Nicotine Adenine Dinucleotide (NADH) to Glycerol-3-Phosphate (G3P) and NAD+. GPDH-C is inhibited by zinc ions and sulfate. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. GPDH-C is unlike Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH); they have different substrates.

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