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Recombinant Human IL-20RB Protein (Fc Tag)

Uniprot : Q6UXL0
  • Cat.No.:PKSH032574

  • Expression host: HEK293 Cells

To Purchase PKSH032574

Size:
  • 10µg
  • 50µg
Price: $263
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Description

Synonyms Interleukin-20 receptor subunit beta, IL-20 receptor subunit beta, IL-20R-beta, IL-20RB, IL-20R2, DIRS1, hCG_2022374, FNDC6, MGC34923, fibronectin type III domain containing 6, interleukin-20 receptor II
Species Human
Expression_host HEK293 Cells
Sequence Asp30-Ala230
Accession Q6UXL0
Mol_Mass 49.6 kDa
AP_Mol_Mass 70 kDa
Tag C-Fc
Bio_Activity Testing in progress

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of PBS, pH 7.4 .
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Not Applicable

Background

Interleukin-20 receptor subunit beta(IL20RB) is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family

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