English Toll-free:1-888-852-8623 or Contact Us
Keyword cannot be empty !

Recombinant Human IL-20RB Protein (Fc Tag)

Cat:PKSH032574
Manual MSDS

Price: $ 447

Price: $ 263

Size:
50μg 10μg
Quantity:
  • Expression Host: HEK293 Cells
  • Accession: Q6UXL0
Add to cart

For research use only. Order now, ship in 3 days

Product Details
Synonyms Interleukin-20 receptor subunit beta;IL-20 receptor subunit beta;IL-20R-beta;IL-20RB;IL-20R2;DIRS1;hCG_2022374;FNDC6;MGC34923;fibronectin type III domain containing 6;interleukin-20 receptor II
Species Human
Expression Host HEK293 Cells
Sequence Asp30-Ala230
Accession Q6UXL0
Calculated Molecular Weight 49.6 kDa
Observed Molecular Weight 60-85 kDa
Tag C-Fc
Purity > 90 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Reconstitution Not Applicable
Background Interleukin-20 receptor subunit beta(IL20RB) is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family