Recombinant Human Interleukin-17D/IL-17D Protein

    • Recombinant Human Interleukin-17D / IL-17D Protein-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human Interleukin-17D / IL-17D Protein-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human Interleukin-17D / IL-17D Protein-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033627

      Synonyms:Interleukin-17D; IL-17D;IL17D

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $129

      Lead Time: Order now, ship in 3 daysWelcome to order from local distributors.

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      Overview

      Synonyms Interleukin-17D; IL-17D;IL17D
      Species Human
      Expression_host E.coli
      Sequence Ala18-Pro202
      Accession Q8TAD2
      Mol_Mass 20.3 kDa
      AP_Mol_Mass 20 kDa

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of 4mM HCl.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      The Interleukin-17 family proteins, comprising six members (IL-17, IL-17B through IL-17F),are secreted, structurally related proteins that share a conserved cysteine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus. IL-17 family proteins are proinflammatory cytokines that induce local cytokine production and are involved in the regulation of immune functions. Among IL-17 family members, IL-17D is most closely related to IL-17B, sharing 27% aa sequence homology. IL-17D is expressed preferentially in skeletal muscle, heart, adipose tissue, lung, pancreas, and nervous system. Like other IL-17 family members, IL-17D modulates immune responses indirectly by stimulating the production of myeloid growth factors and chemokines including IL-6, IL-8, and GM-CSF. IL-17D has also been shown to suppress the proliferation of myeloid progenitors in colony formation assays.

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