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Recombinant Human Interleukin-2/IL-2 Protein (C145S)

Uniprot : P60568
  • Cat.No.:PKSH033623

  • Expression host: E.coli

To Purchase PKSH033623

Size:
  • 10μg
  • 50μg
Price: $62
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Description

Synonyms Interleukin-2;IL-2;T-Cell Growth Factor;TCGF;Aldesleukin;IL6
Species Human
Expression_host E.coli
Sequence Pro22-Thr153(Cys145Ser)
Accession P60568
Application Cell Culture
Mol_Mass 15.5 kDa
AP_Mol_Mass 14 kDa
Tag None
Bio_Activity Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is 90-270 pg/ml

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of 10mM Acetata-Na, 5% Trehaiose, pH 4.5.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.

Background

Interleukin-2(IL-2) is an interleukin; a type of cytokine signaling molecule in the immune system;belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells; NK cells; lymphokine-activated killer cells; monocytes; macrophages and oligodendrocytes.

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