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Recombinant Human Interleukin-2/IL-2 Protein (His Tag)

Uniprot : P60568

Cat.No.:PKSH032629
Expression host: HEK293 Cells

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Description

Synonyms	Interleukin-2;IL-2;T-Cell Growth Factor;TCGF;Aldesleukin;IL4
Species	Human
Expression_host	HEK293 Cells
Sequence	Ala21-Thr153
Accession	P60568
Application	Cell Culture
Mol_Mass	16.4 kDa
AP_Mol_Mass	14-18 kDa
Tag	C-His
Bio_Activity	Measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells The specific activity of Recombinant Human IL-2 is ≥1×10⁷ IU/mg.

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 0.01 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of 10mM Sodium Citrate, 4% Mannitol, pH4.0 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background

Interleukin-2(IL-2) is an interleukin; a type of cytokine signaling molecule in the immune system;belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells; NK cells; lymphokine-activated killer cells; monocytes; macrophages and oligodendrocytes.

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Reviews/Q&A

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Reviews
Q&A

R**********nSubmitted [ Feb 23 2023 ]

Asked: Dear Sir, I have sent a question yesterday about the IU of this rhIL-2 but instead of receiving the answer, I got the website again of the product. Excuse me for the inconvenience. Could you please let me know where i can find the answer? Best regards, Rania

adminSubmitted [ Feb 23 2023 ]

Answered: Dear Rania, Thanks for your question. Please kindly note that the specific activity of PKSH032629 is ≥1×107 IU/mg. If you need any other information, please feel free to tell us. Kind regards,

R**********nSubmitted [ Feb 22 2023 ]

Asked: Dear sir, May I know the IU/mg of this product? Best regards, Rania

adminSubmitted [ Feb 22 2023 ]

Answered: Dear Rania, Thanks for your enquiry. The specific activity of PKSH032629 is ≥1×107 IU/mg. Please let us know if we can be of any further assistance. Best Regards,

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