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Recombinant Human Interleukin-2/IL-2 Protein (His Tag)

Uniprot : P60568

Cat.No.:PKSH032629
Expression host: HEK293 Cells

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Description

Synonyms	Interleukin-2;IL-2;T-Cell Growth Factor;TCGF;Aldesleukin;IL4
Species	Human
Expression_host	HEK293 Cells
Sequence	Ala21-Thr153
Accession	P60568
Application	Cell Culture
Mol_Mass	16.4 kDa
AP_Mol_Mass	14-18 kDa
Tag	C-His
Bio_Activity	Measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells The specific activity of Recombinant Human IL-2 is ≥1×10⁷ IU/mg.

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 0.01 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of 10mM Sodium Citrate, 4% Mannitol, pH4.0 Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the
Reconstitution	Please refer to the printed manual for detailed information.

Background

Interleukin-2(IL-2) is an interleukin; a type of cytokine signaling molecule in the immune system;belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells; NK cells; lymphokine-activated killer cells; monocytes; macrophages and oligodendrocytes.

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Reviews/Q&A

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Reviews
Q&A

R**********nSubmitted [ Feb 23 2023 ]

Asked: Dear Sir, I have sent a question yesterday about the IU of this rhIL-2 but instead of receiving the answer, I got the website again of the product. Excuse me for the inconvenience. Could you please let me know where i can find the answer? Best regards, Rania

adminSubmitted [ Feb 23 2023 ]

Answered: Dear Rania, Thanks for your question. Please kindly note that the specific activity of PKSH032629 is ≥1×107 IU/mg. If you need any other information, please feel free to tell us. Kind regards,

R**********nSubmitted [ Feb 22 2023 ]

Asked: Dear sir, May I know the IU/mg of this product? Best regards, Rania

adminSubmitted [ Feb 22 2023 ]

Answered: Dear Rania, Thanks for your enquiry. The specific activity of PKSH032629 is ≥1×107 IU/mg. Please let us know if we can be of any further assistance. Best Regards,

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