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Recombinant Human/Mouse/Rat BDNF Protein (Active)

    • Recombinant Human / Mouse / Rat BDNF Protein-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human / Mouse / Rat BDNF Protein-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human / Mouse / Rat BDNF Protein-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033808

      Synonyms:Brain-Derived Neurotrophic Factor; BDNF; Abrineurin

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $178

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      Overview

      Synonyms Brain-Derived Neurotrophic Factor; BDNF; Abrineurin
      Species Human/Mouse/Rat
      Expression_host E.coli
      Sequence His129-Arg247
      Accession P23560
      Application Functional ELISA
      Mol_Mass 13 kDa
      AP_Mol_Mass 14 kDa
      Bio_Activity Immobilized Human BDNF at 2ug/mll(100 μl/well) can bind Human TrkB-His(Cat: PKSH033579). The ED50 of Human BDNF is 2-10 ug/ml .

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 250mM NaCl, pH 7.2.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease.

      Image

      Immobilized Human BDNF at 2ug/mll(100 μl/well) can bind Human TrkB-His(Cat: PKSH033579). The ED50 of Human BDNF is 2-10 ug/ml .

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      MSDS for ELISA ISO 9001

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