Recombinant Human PD-L1/B7-H1/CD274 Protein (Fc & Avi Tag)

    • Recombinant Human PD-L1 / B7-H1 / CD274 Protein (C-Fc-Avi)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human PD-L1 / B7-H1 / CD274 Protein (C-Fc-Avi)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human PD-L1 / B7-H1 / CD274 Protein (C-Fc-Avi)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033796

      Synonyms:Programmed Cell Death 1 Ligand 1; PD-L1; PDCD1 ligand 1; Programmed death ligand 1; B7 homolog 1; B7-H1; CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1

      Size:
      • 20μg
      • 100μg
      Qty:
      - +
      Price: $342

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      Overview

      Synonyms Programmed Cell Death 1 Ligand 1; PD-L1; PDCD1 ligand 1; Programmed death ligand 1; B7 homolog 1; B7-H1; CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
      Species Human
      Expression_host Human Cells
      Sequence Phe19-Thr239
      Accession Q9NZQ7
      Mol_Mass 54.2 kDa
      AP_Mol_Mass 70-95 kDa
      Tag C-Fc-Avi

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. By binding to PD1 on activated T-cells and B-cells, PD-L1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression. Accordingly, it leads to growth of immunogenic tumor growth by increasing apoptosis of antigen specific T cells and may contribute to immune evasion by cancers. PD-L1 thus is regarded as promising therapeutic target for human autoimmune disease and malignant cancers.

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      MSDS for ELISA ISO 9001

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