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Recombinant Human PD-L1/B7-H1/CD274 Protein (Flag Tag)

Uniprot : Q9NZQ7
  • Cat.No.:PKSH032870

  • Expression host: HEK293 Cells

To Purchase PKSH032870

  • 10μg
  • 50μg
Price: $80


Synonyms Programmed Cell Death 1 Ligand 1;PD-L1;PDCD1 Ligand 1;Programmed Death Ligand 1;B7 Homolog 1;B7-H1;CD274;B7H1;PDCD1L1;PDCD1LG1;PDL1
Species Human
Expression_host HEK293 Cells
Sequence Phe19-Thr 239
Accession Q9NZQ7
Mol_Mass 26.3 kDa
AP_Mol_Mass 35-40 kDa
Tag C-Flag


Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed man
Reconstitution Please refer to the printed manual for detailed information.


CD274; also known as B7-H1 or programmed death ligand 1 (PD-L1); is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. Programmed death-1 ligand-1 (PD-L1; CD274; B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. By binding to PD1 on activated T-cells and B-cells; PD-L1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression. Accordingly; it leads to growth of immunogenic tumor growth by increasing apoptosis of antigen specific T cells and may contribute to immune evasion by cancers. PD-L1 thus is regarded as promising therapeutic target for human autoimmune disease and malignant cancers.

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