Recombinant Human TIM-3/HAVCR2 Protein (His Tag)(Active)

    • Recombinant Human TIM-3 / HAVCR2 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human TIM-3 / HAVCR2 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human TIM-3 / HAVCR2 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033509

      Synonyms:Hepatitis A Virus Cellular Receptor 2; HAVcr-2; T-Cell Immunoglobulin and Mucin Domain-Containing Protein 3; TIMD-3; T-Cell Membrane Protein 3; TIM-3; HAVCR2; TIM3; TIMD3

      Size:
      • 10μg
      • 50μg
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      Price: $86

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      Overview

      Synonyms Hepatitis A Virus Cellular Receptor 2; HAVcr-2; T-Cell Immunoglobulin and Mucin Domain-Containing Protein 3; TIMD-3; T-Cell Membrane Protein 3; TIM-3; HAVCR2; TIM3; TIMD3
      Species Human
      Expression_host Human Cells
      Sequence Ser22-Arg200 (Arg140Leu)
      Accession Q8TDQ0
      Application Functional ELISA
      Mol_Mass 20.86 kDa
      AP_Mol_Mass 37 kDa
      Tag C-His
      Bio_Activity Immobilized Human Galectin-9-GST at 2μg/ml(100 μl/well) can bind Human TIM-3-His.

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      T-Cell Membrane Protein 3 (TIM3) is a single-pass type I membrane protein that belongs to the TIM family of immunoglobulin superfamily. TIM3 includes a signal sequence (aa 1-21), an extracellular region (aa 22-202) with one Ig-like V-type domain, a transmembrane segment (aa 203-223), and a cytoplasmic domain (aa 224 - 301). TIM3 regulates macrophage activation, inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. It may be also involved in T-cell homing and as a receptor for LGALS9.

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      MSDS for ELISA ISO 9001

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