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Recombinant Human TrkB/NTRK2 Protein (His Tag)

Cat:PKSH033579
Manual MSDS

Price: $ 148

Price: $ 49

Size:
50μg 10μg
Quantity:
  • Expression Host: HEK293 Cells
  • Accession: Q16620
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Product Details
Synonyms BDNF/NT-3 Growth Factors Receptor;GP145-TrkB;Trk-B;Neurotrophic Tyrosine Kinase Receptor Type 2;TrkB Tyrosine Kinase;Tropomyosin-Related Kinase B;NTRK2;TRKB
Species Human
Expression Host HEK293 Cells
Sequence Cys32-His430
Accession Q16620
Calculated Molecular Weight 45.3 kDa
Observed Molecular Weight 60-105 kDa
Tag C-His
Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.
Background The TRK Family of Tyrosine Kinase Receptor consists of 3 members: TrkA, TrkB and TrkC. The three TRK family proteins have different ligand specificities. They connect to different neurotrophins, including NGF, BDNF, NT-3NT-4/5. TRKA binds NGF, TRKB binds BDNF and NT-3, TRKC binds NT-4/5. At the protein sequence level, human and rat TRKB have greater than 90% sequence identity and the proteins exbihit cross-species activity. TRKB is primarily expressed in the nervous system and it also expression in a wide variety of tissues with low levels.