Recombinant Human TrkB/NTRK2 Protein (His Tag)(Active)

    • Recombinant Human TrkB / NTRK2 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human TrkB / NTRK2 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human TrkB / NTRK2 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033579

      Synonyms:BDNF/NT-3 Growth Factors Receptor; GP145-TrkB; Trk-B; Neurotrophic Tyrosine Kinase Receptor Type 2; TrkB Tyrosine Kinase; Tropomyosin-Related Kinase B; NTRK2; TRKB

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      • 10μg
      • 50μg
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      Price: $49

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      Overview

      Synonyms BDNF/NT-3 Growth Factors Receptor; GP145-TrkB; Trk-B; Neurotrophic Tyrosine Kinase Receptor Type 2; TrkB Tyrosine Kinase; Tropomyosin-Related Kinase B; NTRK2; TRKB
      Species Human
      Expression_host Human Cells
      Sequence Cys32-His430
      Accession Q16620
      Application Functional ELISA
      Mol_Mass 45.25 kDa
      AP_Mol_Mass 60-105 kDa
      Tag C-His
      Bio_Activity Immobilized Human NT-3(Cat: PKSH032803) at 2μg/ml(100 μl/well) can bind Human TrkB-His. The ED50 of Human TrkB-His is 3.777ug/ml .

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      The TRK Family of Tyrosine Kinase Receptor consists of 3 members: TrkA, TrkB and TrkC. The three TRK family proteins have different ligand specificities. They connect to different neurotrophins, including NGF, BDNF, NT-3NT-4/5. TRKA binds NGF, TRKB binds BDNF and NT-3, TRKC binds NT-4/5. At the protein sequence level, human and rat TRKB have greater than 90% sequence identity and the proteins exbihit cross-species activity. TRKB is primarily expressed in the nervous system and it also expression in a wide variety of tissues with low levels.

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      MSDS for ELISA ISO 9001

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