Recombinant Human XRCC5 & XRCC6 Heterodimer Protein

    • Recombinant Human XRCC5 & XRCC6 Heterodimer Protein-Elabscience
    • Recombinant protein products for various applications-Elabscience
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    • Recombinant Human XRCC5 & XRCC6 Heterodimer Protein-Elabscience
    • Recombinant protein products for various applications-Elabscience
    • Recombinant Human XRCC5 & XRCC6 Heterodimer Protein-Elabscience
    • Recombinant protein products for various applications-Elabscience

      Catalog number:PKSH030480

      Synonyms:KARP-1;KARP1;KU80;Ku86;KUB2;NFIV

      Size:
      • 20 μg
      • 50 μg
      Qty:
      - +
      Price: $365

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms KARP-1;KARP1;KU80;Ku86;KUB2;NFIV
      Species Human
      Expression_host Baculovirus-Insect Cells
      Sequence Met 1-Ile 732
      Accession P13010
      Mol_Mass 157 (85 + 72) kDa
      AP_Mol_Mass 70 & 85 kDa

      Properties

      Purity > 90 % as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per µg as determined by the LAL method.
      Storage Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from sterile 20mM Tris, 500mM NaCl, 10% gly, pH 8.0
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      X-ray repair cross-complementing protein 5, also known as 86 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 80 kDa subunit, CTC box-binding factor 85 kDa subunit, DNA repair protein XRCC5, Lupus Ku autoantigen protein p86, TLAA and XRCC5, is a nucleus and chromosome which belongs to the ku80 family. XRCC5 is a single stranded DNA-dependent ATP-dependent helicase. XRCC5 has a role in chromosome translocation.  X-ray repair cross-complementing protein 6, also known as 5'-deoxyribose-5-phosphate lyase Ku70, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, CTC box-binding factor 75 kDa subunit, Lupus Ku autoantigen protein p70, Thyroid-lupus autoantigen and XRCC6, is a nucleus and chromosome which belongs to the ku70 family. Heterodimer of a XRCC6 and a XRCC5 subunit associates in a DNA-dependent manner with PRKDC to form the DNA-dependent protein kinase complex DNA-PK, and with the LIG4-XRCC4 complex. The dimer also associates with NAA15, and this complex binds to the osteocalcin promoter and activates osteocalcin expression. 

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