English Toll-free:1-888-852-8623 or Contact Us
Keyword cannot be empty !

Recombinant Mouse CD300a/LMIR1 Protein (Fc Tag)

Cat:PKSM041101
Manual MSDS

Price: $ 339

Price: $ 117

Size:
50μg 10μg
Quantity:
  • Expression Host: HEK293 Cells
  • Accession: Q6SJQ0
Add to cart

For research use only. Order now, ship in 3 days

Product Details
Synonyms CD300a;CD300a antigen;CMRF35H9;CD300a molecule;leukocyte immunoglobulin-like receptor;CD300 antigen-like family member A;CMRF35-like molecule 8;NK inhibitory receptor;Immunoglobulin superfamily member 12;IRp60;Inhibitory receptor protein 60;CLM8;CMRF-35H;IGSF12;IRC1;IRC2;LMIR1;CLM-8;MAIR-I;Clm8;MAIR-I;MAIR-Ia;mcpir1;MMAC8;Pigr4
Species Mouse
Expression Host HEK293 Cells
Sequence Leu28-Arg183
Accession Q6SJQ0
Calculated Molecular Weight 44.3 kDa
Observed Molecular Weight 58-75 kDa
Tag C-Fc
Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.
Background LMIR1, also termed CD300a, is a type I transmembrane glycoprotein with a single IgV-like extracellular domain and an extended membrane proximal region that links the immunoglobulin (Ig) and transmembrane domains and belongs to the immunoglobulin superfamily. The intracellular domain of LMIR1 contains several immunoreceptor tyrosine-based inhibition motifs (ITIMs). When cross-linked, it will be tyrosine phosphorylated and capable of recruiting tyrosine phosphatases (SHP-1, SHP-2) and inositol polyphosphate 5-phosphatase, SHIP. LMIR1 will regulate mast cell-mediated inflammatory responses. LMIR1 is broadly expressed on myeloid and lymphoid cells, and its expression is differentially regulated depending on the cell type.