Recombinant Mouse CD86/B7-2 Protein (His Tag)

    • Recombinant Mouse B7-2 / CD86 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Mouse B7-2 / CD86 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Mouse B7-2 / CD86 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSM041272

      Synonyms:T-lymphocyte activation antigen CD86; Activation B7-2 antigen; Early T-cell costimulatory molecule 1; ETC-1; CD86;B7;B7-2;B7.2;B70;Cd28l2;CLS1;ETC-1;Ly-58;Ly58;MB7;MB7-2;TS/A-2

      Size:
      • 10μg
      • 50μg
      Qty:
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      Price: $62

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      Overview

      Synonyms T-lymphocyte activation antigen CD86; Activation B7-2 antigen; Early T-cell costimulatory molecule 1; ETC-1; CD86;B7;B7-2;B7.2;B70;Cd28l2;CLS1;ETC-1;Ly-58;Ly58;MB7;MB7-2;TS/A-2
      Species Mouse
      Expression_host Human Cells
      Sequence Val24-Lys244
      Accession P42082
      Mol_Mass 25.9 kDa
      AP_Mol_Mass 35-85 kDa
      Tag C-His

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. Mouse CD86 shares 59% and 81% aa sequence identity with human and rat CD86, respectively. It contains 1 Ig-like C2-type domainand 1 Ig-like V-type domain. It is highly expressed on activated antigen presenting cells. CD86 involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation.

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      MSDS for ELISA ISO 9001

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