Recombinant Mouse Clusterin/ApoJ Protein (His Tag)

    • Recombinant Mouse  Clusterin Protein (His Tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
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    • Recombinant Mouse  Clusterin Protein (His Tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
    • Recombinant Mouse  Clusterin Protein (His Tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience

      Catalog number:PKSM040656

      Synonyms:Clusterin;Apolipoprotein J;Clustrin;Sulfated glycoprotein 2;ApoJ; Cli; D14Ucla3; Sgp-2; Sgp2; SP-40;Sugp-2

      Size:
      • 50 μg
      • 100 μg
      Qty:
      - +
      Price: $454

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms Clusterin;Apolipoprotein J;Clustrin;Sulfated glycoprotein 2;ApoJ; Cli; D14Ucla3; Sgp-2; Sgp2; SP-40;Sugp-2
      Species Mouse
      Expression_host HEK293 Cells
      Sequence Met 1-Glu 448
      Accession NP_038520.2
      Mol_Mass 50.8 kDa
      Tag C-His

      Properties

      Purity > 96 % as determined by SDS-PAGE
      Endotoxin < 1.0 EU per µg of the protein as determined by the LAL method.
      Storage Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from sterile PBS, pH 7.4
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted protein which belongs to the clusterin family. Clusterin/Apolipoprotein J/Apo-J is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution and an apparent involvement in biological processes ranging from mammary gland involution to neurodegeneration in Alzheimer's disease. Its major form, a heterodimer, is secreted and present in physiological fluids, but truncated forms targeted to the nucleus have also been identified. Clusterin/Apolipoprotein J/Apo-J is a widely distributed glycoprotein with a wide range of biologic properties. A prominent and defining feature of clusterin is its marked induction in such disease states as glomerulonephritis, cystic renal disease, renal tubular injury, neurodegenerative conditions, atherosclerosis, and myocardial infarction. Upregulation of clusterin mRNA and protein levels detected in diverse disease states and in in vitro systems have led to suggestions that it functions in membrane lipid recycling, in apoptotic cell death, and as a stress-induced secreted chaperone protein, amongst others.

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