Recombinant Mouse Hemopexin/HPX Protein (His Tag)

    • Recombinant Mouse Hemopexin Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Mouse Hemopexin Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Mouse Hemopexin Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSM041334

      Synonyms:Hemopexin;Hpx;Hpxn

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $257

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      Overview

      Synonyms Hemopexin;Hpx;Hpxn
      Species Mouse
      Expression_host Human Cells
      Sequence Ser24-Gln460
      Accession Q91X72
      Mol_Mass 49.8 kDa
      AP_Mol_Mass 65-90 kDa
      Tag C-His

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
      Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice.Upon receipt, store it immediately at<-20°C.
      Formulation Supplied as a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, pH 5.5.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Hemopexin (HPX) is plasma glycoprotein belongs to the family of the acute-phase proteins whose synthesis is induced after an inflammatory event. Hemopexin with two four-bladed beta -propeller folds has been found in other proteins including collagenases and provides sites for protein-protein interactions. The liver is the major synthesizing organ. Hemopexin participates in maintaining and recycling the iron pool by utilizing its high binding affinity toward heme composed of protoporphyrin IX and iron. It also functions in preventing oxidation caused by heme after hemolysis. Hydrophobic heme molecules can intercalate into lipid membranes and participate in the oxidation of lipid membrane components through the Fenton reaction resulting in lipid peroxidation. Hemopexin undergoes a conformational change upon the binding of heme. The conformational change allows hemopexin to interact with a specific receptor, forming a complex which is then internalized. Heme concentrations in plasma increase after hemolysis, which is associated with several pathological conditions such as reperfusion injury and ischemia.

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      MSDS for ELISA ISO 9001

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