Recombinant Mouse Lumican/LUM Protein (His Tag)

    • Recombinant Mouse Lumican / LUM  Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Mouse Lumican / LUM  Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Mouse Lumican / LUM  Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSM041313

      Synonyms:Keratan sulfate proteoglycan lumican;KSPG lumican;Lumican; LDC

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $129

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      Overview

      Synonyms Keratan sulfate proteoglycan lumican;KSPG lumican;Lumican; LDC
      Species Mouse
      Expression_host Human Cells
      Sequence Gln19-Asn338
      Accession P51885
      Mol_Mass 37.4 kDa
      AP_Mol_Mass 40-60 kDa
      Tag C-His

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of PBS,pH 7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Keratan sulfate proteoglycan lumican, mostly known as lumican, belongs to the SLRP class II subfamily and the small leucine-rich proteoglycan (SLRP) family. Lumican binds to laminin. It has positive regulation of transcription from RNA polymerase II promoter and transforming growth factor beta1 production. Lumican is expressed in a variety of tissues, including skin, artery, lung, cornea, kidney, bone, aorta, and articular cartilage. The abnormal connective tissue phenotype seen in the Lumican null mice shows the importance of the role of Lumican in collagen fibrillogenesis. In addition to the control of collagen fibril assembly, Lumican has been shown to play a role in the regulation of cell proliferation, migration, and adhesion.

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