Recombinant Mouse OX40/TNFRSF4 Protein (Fc Tag)(Active)

    • Recombinant Mouse OX40 / TNFRSF4 Protein (C-Fc)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Mouse OX40 / TNFRSF4 Protein (C-Fc)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Mouse OX40 / TNFRSF4 Protein (C-Fc)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSM041298

      Synonyms:Tumor necrosis factor receptor superfamily member 4;Tnfrsf4;OX40;CD134;Txgp1

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $117

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      Overview

      Synonyms Tumor necrosis factor receptor superfamily member 4;Tnfrsf4;OX40;CD134;Txgp1
      Species Mouse
      Expression_host Human Cells
      Sequence Val20-Pro211
      Accession P47741
      Application Functional ELISA
      Mol_Mass 48.1 kDa
      AP_Mol_Mass 65-90 kDa
      Tag C-Fc
      Bio_Activity Immobilized Mouse OX40L-His(Cat: PKSM041119) at 2μg/ml(100 μl/well) can bind Mouse OX40-Fc. The ED50 of Mouse OX40-Fc is 4.204 ug/ml .

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation by CD40-CD40 Ligand and CD28-B7. The interaction between OX40 and OX40 ligand (OX40L) will occur when activated T cells bind to professional antigen-presenting cells (APCs). The T-cell functions, including cytokine production, expansion, and survival, are then enhanced by the OX40 costimulatory signals. OX40 signals are critical for controlling the function and differentiation of Foxp3+ regulatory T cells. OX40-OX40L interaction regulates T-cell tolerance, peripheral T-cell homeostasis, and T-cell-mediated inflammatory diseases.

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      MSDS for ELISA ISO 9001

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