Recombinant Mouse PDGF-BB Protein (His Tag)(Active)

    • Recombinant Mouse PDGF-BB Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Mouse PDGF-BB Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Mouse PDGF-BB Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSM041293

      Synonyms:Platelet-Derived Growth Factor Subunit B; PDGF Subunit B; PDGF-2; Platelet-Derived Growth Factor B Chain; Platelet-Derived Growth Factor Beta Polypeptide; Proto-Oncogene c-Sis; Becaplermin; PDGFB; PDGF2; SIS

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $129

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      Overview

      Synonyms Platelet-Derived Growth Factor Subunit B; PDGF Subunit B; PDGF-2; Platelet-Derived Growth Factor B Chain; Platelet-Derived Growth Factor Beta Polypeptide; Proto-Oncogene c-Sis; Becaplermin; PDGFB; PDGF2; SIS
      Species Mouse
      Expression_host E.coli
      Sequence Ser82-Thr190
      Accession P31240
      Application Cell Culture
      Mol_Mass 13.4 kDa
      AP_Mol_Mass 14 kDa
      Tag C-His
      Bio_Activity Measured in a cell proliferation assay using Balb/c3T3 mouse fibroblast cells. The ED50 for this effect is 1.55 ng/ml.

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of 4mM HCl.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. As growth factor,it plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. It is required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. PDGFB also plays an important role in wound healing.

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