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Recombinant Mouse TIM1/HAVCR1 Protein (His & Fc Tag)

Cat:PKSM040735
Manual MSDS

Price: $ 855

Size:
100μg
Quantity:
  • Expression Host: HEK293 Cells
  • Accession: NP_001160104.1
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For research use only. Order now, ship in 3 days

Product Details
Synonyms Hepatitis A virus cellular receptor 1 homolog;HAVcr-1;Kidney injury molecule 1;KIM-1;T cell membrane protein 1;TIM-1;Timd1;AI503787
Species Mouse
Expression Host HEK293 Cells
Sequence Tyr 22-Thr 212
Accession NP_001160104.1
Calculated Molecular Weight 49.0 kDa
Observed Molecular Weight 80-85 kDa
Tag C-His-Fc
Purity > 97 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from sterile 20mM Tris-Citrate, 150mM NaCl, pH 6.5
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.
Background HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulinmucin 1 (TIM-1), is a type &acirc;&hellip; integral membrane glycoprotein. KIM-1 protein is widely expressed with highest levels in kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling.