Recombinant Mouse TIM1/HAVCR1 Protein (His & Fc Tag)
Price: $ 855
Size:
100μg
Quantity:
- Expression Host: HEK293 Cells
- Accession: NP_001160104.1
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For research use only. Order now, ship in 3 days
Product Details
Synonyms | Hepatitis A virus cellular receptor 1 homolog;HAVcr-1;Kidney injury molecule 1;KIM-1;T cell membrane protein 1;TIM-1;Timd1;AI503787 |
Species | Mouse |
Expression Host | HEK293 Cells |
Sequence | Tyr 22-Thr 212 |
Accession | NP_001160104.1 |
Calculated Molecular Weight | 49.0 kDa |
Observed Molecular Weight | 80-85 kDa |
Tag | C-His-Fc |
Purity | > 97 % as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation |
Lyophilized from sterile 20mM Tris-Citrate, 150mM NaCl, pH 6.5 Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Reconstitution | Please refer to the printed manual for detailed information. |
Background | HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulinmucin 1 (TIM-1), is a type â… integral membrane glycoprotein. KIM-1 protein is widely expressed with highest levels in kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling. |