Recombinant Mouse TSLP Protein (His Tag)
Price: $ 779
Price: $ 4339
Size:
100μg
1mg
Quantity:
- Expression Host: HEK293 Cells
- Accession: Q9JIE6
- Applications: ELISA
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Product Details
Synonyms | Thymic stromal lymphopoietin;Thymic stroma-derived lymphopoietin;Tslp;TSLP |
Species | Mouse |
Expression Host | HEK293 Cells |
Sequence | Met 1-Glu 140 |
Accession | Q9JIE6 |
Calculated Molecular Weight | 15.4 kDa |
Observed Molecular Weight | 22-27 kDa |
Tag | C-His |
Bio-activity | Measured by its ability to bind human IL7RA-his in functional ELISA. |
Purity | > 90 % as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation |
Lyophilized from sterile PBS, pH 7.4 Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Reconstitution | Please refer to the printed manual for detailed information. |
Background | Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is a cytokine expressed by epithelial cells, including keratinocytes, and is important in allergic inflammation. Subsequent studies have shown that TSLP promotes T helper type 2 (TH2) cell responses associated with immunity to some helminth parasites and the pathogenesis of many inflammatory diseases, including atopic dermatitis and asthma. TSLP can promote TH2 cytokine-associated inflammation by directly promoting the effector functions of CD4+ TH2 cells, basophils and other granulocyte populations while simultaneously limiting the expression of DC-derived proinflammatory cytokines and promoting regulatory T cell responses in peripheral tissues. |