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Recombinant Mouse TSLP Protein (His Tag)

Cat:PKSM040390
Manual MSDS

Price: $ 779

Price: $ 4339

Size:
100μg 1mg
Quantity:
  • Expression Host: HEK293 Cells
  • Accession: Q9JIE6
  • Applications: ELISA
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Product Details
Synonyms Thymic stromal lymphopoietin;Thymic stroma-derived lymphopoietin;Tslp;TSLP
Species Mouse
Expression Host HEK293 Cells
Sequence Met 1-Glu 140
Accession Q9JIE6
Calculated Molecular Weight 15.4 kDa
Observed Molecular Weight 22-27 kDa
Tag C-His
Bio-activity Measured by its ability to bind human IL7RA-his in functional ELISA.
Purity > 90 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.
Background Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is a cytokine expressed by epithelial cells, including keratinocytes, and is important in allergic inflammation. Subsequent studies have shown that TSLP promotes T helper type 2 (TH2) cell responses associated with immunity to some helminth parasites and the pathogenesis of many inflammatory diseases, including atopic dermatitis and asthma. TSLP can promote TH2 cytokine-associated inflammation by directly promoting the effector functions of CD4+ TH2 cells, basophils and other granulocyte populations while simultaneously limiting the expression of DC-derived proinflammatory cytokines and promoting regulatory T cell responses in peripheral tissues.