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Recombinant Rhesus macaque CD47/IAP Protein (Fc Tag)

Uniprot : F7A802

Cat.No.:PKSQ050076
Expression host: HEK293 Cells

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Description

Synonyms	Leukocyte Surface Antigen CD47;Antigenic Surface Determinant Protein OA3;Integrin-Associated Protein;IAP;Protein MER6;CD47;MER6
Species	Rhesus macaque
Expression_host	HEK293 Cells
Sequence	Gln19-Pro139
Accession	F7A802
Mol_Mass	40.8 kDa
AP_Mol_Mass	60-90 kDa
Tag	C-Fc

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCl, 100 mM Glycine, pH 7.5. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the
Reconstitution	Please refer to the printed manual for detailed information.

Background

CD47(Integrin-Associated Protein,IAP) is a 40 ? 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes.

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