RICTOR Polyclonal Antibody

Uniprot : Q6R327
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14684

      Synonyms:AVO3,AVO3 homolog,DKFZp686B11164,hAVO3,KIAA1999,Likely ortholog of mouse TORC2 specific protein AVO3 (S. cerevisiae),mAVO3,MGC39830,PIA,Pianissimo,Rapamycin insensitive companion of mTOR,Rapamycin-insensitive companion of mTOR,Rictor,RICTR,RICTR,RPTOR independent companion of MTOR complex 2,TORC2 specific protein AVO3

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms AVO3,AVO3 homolog,DKFZp686B11164,hAVO3,KIAA1999,Likely ortholog of mouse TORC2 specific protein AVO3 (S. cerevisiae),mAVO3,MGC39830,PIA,Pianissimo,Rapamycin insensitive companion of mTOR,Rapamycin-insensitive companion of mTOR,Rictor,RICTR,RICTR,RPTOR independent companion of MTOR complex 2,TORC2 specific protein AVO3
      Swissprot Q6R327
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human RICTOR
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:50-1:200
      Concentration 0.3 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytosol,Other locations:TORC2 complex
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background Rapamycin-insensitive companion of mTOR is a protein that in humans is encoded by the RICTOR gene. RICTOR and MTOR are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth. Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors.

      Images

      Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using RICTOR Polyclonal Antibody at dilution 1:40

      Immunohistochemistry of paraffin-embedded Human liver cancer tissue using RICTOR Polyclonal Antibody at dilution 1:40

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