RNF7 Polyclonal Antibody (E-AB-61633)

For research use only.
Verified Samples |
Verified Samples in IF: MCF-7 |
Dilution | IF 1:20-1:50 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human |
Applications | IF |
Clonality | Polyclonal |
Immunogen | Recombinant fusion protein of human RNF7 (NP_055060.1). |
Abbre | RNF7 |
Synonyms | CKBBP1, RNF7, ROC2, SAG |
Swissprot | |
Cellular Localization | Cytoplasm. Nucleus. |
Concentration | 1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. |
Other Clones
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Other Formats
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Unconjugated
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