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For research use only.

Verified Samples Verified Samples in IF: MCF-7
Dilution IF 1:20-1:50
Isotype IgG
Host Rabbit
Reactivity Human
Applications IF
Clonality Polyclonal
Immunogen Recombinant fusion protein of human RNF7 (NP_055060.1).
Abbre RNF7
Synonyms CKBBP1,  RNF7,  ROC2,  SAG
Swissprot
Cellular Localization Cytoplasm. Nucleus.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology,  Epigenetics and Nuclear Signaling,  Metabolism
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.
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Unconjugated

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