S100A8 Polyclonal Antibody
- +4
Price: $ 530
Price: $ 320
Price: $ 200
Size:
200μL
120μL
60μL
Quantity:
- Host: Rabbit
- Reactivity: Human;Mouse;Rat
- Applications: IHC;IF
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Product Details
Verified Samples |
Verified Samples in IHC:Human tonsil,Human liver,Human skin,Mouse spleen Verified Samples in IF:Human skin cancer, U-2OS |
Dilution |
IHC 1:50-1:100, IF 1:50-1:100 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Recombinant fusion protein of human S100A8 (NP_002955.2). |
Abbre | S100A8 |
Synonyms | S100A8;60B8AG;CAGA;CFAG;CGLA;CP-10;L1Ag;MA387;MIF;MRP8;NIF;P8 |
Swissprot | |
Cellular Localization | Secreted. Cytoplasm. Cytoplasm>cytoskeleton. Cell membrane. Associates with tubulin filaments in activated monocytes. Targeted to the cell surface upon calcium influx. Released from blood leukocytes upon exposure to CSF2/GM-CSF, bacterial lipopolysaccharide (LPS) and during inflammatory processes. Serum levels are high in patients suffering from chronic inflammation. |
Concentration | 1mg/mL |
Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method | Affinity purification |
Research Areas | Cancer; Neuroscience |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Ice bag |
background | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene. |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol