TKTL1 Polyclonal Antibody (E-AB-17097)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human liver cancer, Human esophagus cancer |
| Dilution | IHC 1:30-150 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human TKTL1 |
| Abbre | TKTL1 |
| Synonyms | TK 2, TK2, TKR, TKT 2, TKT2, TKTL1, Transketolase 2, Transketolase like 1, Transketolase like protein 1, Transketolase related protein, Transketolase-like protein 1, Transketolase-related protein, Transketolase2, transketolase-like 1 |
| Swissprot | |
| Cellular Localization | Cytoplasm. Nucleus. Predominantly cytoplasmic and to a lesser extent also nuclear. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome. Three transcript variants encoding different isoforms have been found for this gene. |
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