ALDH4A1 Polyclonal Antibody (E-AB-14536)
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For research use only.
Verified Samples |
Verified Samples in WB: Human liver Verified Samples in IHC: Human colon cancer, Human breast cancer |
Dilution | WB 1:500-1:2000, IHC 1:25-1:100 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | WB, IHC |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human ALDH4A1 |
Abbre | ALDH4A1 |
Synonyms | AL4A1, ALDH4, Aldehyde dehydrogenase, Aldehyde dehydrogenase family 4 member A1, Delta 1 pyrroline 5 carboxylate dehydrogenase, Delta-1-pyrro, aldehyde dehydrogenase 4, aldehyde dehydrogenase 4 family, aldh4a1, family 4, member 1, member A1, mitochondrial, subfamily A |
Swissprot | |
Calculated MW | 62 kDa |
Cellular Localization | Mitochondrion matrix. |
Concentration | 0.3 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Metabolism, Signal Transduction, Tags and Cell Markers |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. |
Other Clones
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Unconjugated
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