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For research use only.

Verified Samples Verified Samples in WB: Human liver
Verified Samples in IHC: Human colon cancer, Human breast cancer
Dilution WB 1:500-1:2000,  IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human ALDH4A1
Abbre ALDH4A1
Synonyms AL4A1,  ALDH4,  Aldehyde dehydrogenase,  Aldehyde dehydrogenase family 4 member A1,  Delta 1 pyrroline 5 carboxylate dehydrogenase,  Delta-1-pyrro,  aldehyde dehydrogenase 4,  aldehyde dehydrogenase 4 family,  aldh4a1,  family 4,  member 1,  member A1,  mitochondrial,  subfamily A
Swissprot
Calculated MW 62 kDa
Cellular Localization Mitochondrion matrix.
Concentration 0.3 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Metabolism,  Signal Transduction,  Tags and Cell Markers
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Other Clones

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Unconjugated

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