ALDOB Polyclonal Antibody (E-AB-12963)
For research use only.
| Verified Samples |
Verified Samples in WB: Mouse liver Verified Samples in IHC: Human cervical cancer, Human esophagus cancer |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ALDOB |
| Synonyms | ALDB, ALDO B, ALDO2, ALDOB, Aldolase 2, Aldolase B, Aldolase B fructose bisphosphate, Aldolase2, AldolaseB, EC 4.1.2.13, Fructose bisphosphate aldolase B, Fructose-bisphosphate aldolase B, Liver type aldolase, Liver-type aldolase, MS1077 |
| Swissprot | |
| Calculated MW | 39 kDa |
| Cellular Localization | Cytoskeleton, centriolar satellite, microtubule organizing center, Cytosol, Extracellular region or secreted, extracellular exosome. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. |
Other Clones
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Unconjugated
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