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For research use only.

Verified Samples Verified Samples in WB: Human fetal muscle, K562, Hela
Verified Samples in IHC: Human liver cancer, Human lung cancer
Dilution WB 1:1000-1:5000,  IHC 1:100-1:300
Isotype IgG
Host Rabbit
Reactivity Human
Applications WB,  IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human AMPD1
Abbre AMPD1
Synonyms AMP deaminase 1,  AMP deaminase isoform M,  AMPD,  AMPD 1,  Adenosine monophosphate deaminase 1,  Adenosine monophosphate deaminase 1 (isoform M),  Ampd01,  MAD,  MADA,  Myoadenylate deaminase,  RATAMPD01,  Skeletal muscle AMPD
Swissprot
Calculated MW 90 kDa
Cellular Localization Cytosol
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Metabolism,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Other Clones

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Unconjugated

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