ATP7A Polyclonal Antibody (E-AB-16268)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human liver cancer, Human breast cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ATP7A |
| Abbre | ATP7A |
| Synonyms | ATP 7A, ATP7A, ATPase Cu++ transporting alpha polypeptide, ATPase Cu++ transporting alpha polypeptide (Menkes syndrome), ATPase copper transporting alpha polypeptide, Copper pump 1, Copper transporting ATPase 1, Copper-transporting ATPase 1, Cu++ transporti |
| Swissprot | |
| Cellular Localization | Endoplasmic reticulum, Cytoplasm>cytosol and Golgi apparatus>trans-Golgi network membrane, Cell membrane, Cycles constitutively between the trans-Golgi network (TGN) and the plasma membrane, Predominantly found in the TGN and relocalized to the plasma membrane in response to elevated copper levels. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Neuroscience, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed. |
Other Clones
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Other Formats
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Unconjugated
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