BAFF R/TNFRSF13C Monoclonal Antibody(Capture/Detector) (AN002530P)
For research use only.
| Verified Samples | Verified Samples in ELISA: Recombinant Human BAFF R/TNFRSF13C protein, Human serum, Human plasma |
| Dilution | ELISA Capture 2-8 μg/mL, ELISA Detector 0.1-0.4 μg/mL |
| Isotype | Rat IgG1 |
| Host | Rat |
| Reactivity | Human |
| Applications | ELISA Capture/Detector |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human BAFF R/TNFRSF13C protein expressed by Mammalian |
| Abbre | BAFF R/TNFRSF13C |
| Synonyms | TNFRSF13C, BAFF-R, BROMIX, CD268, CVID4, Prolixin, Tumor Necrosis Factor Receptor Superfamily Member 13C, |
| Swissprot | |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
| Purification Method | Protein A/G Purification |
| Research Areas | Cancer, Signal transduction |
| Clone No. | 6F7 |
| Conjugation | Unconjugated |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
| background | B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. |
Other Clones
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