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For research use only.

Host Mouse
Reactivity Human
Applications IHC-P
Synonyms CD74
Cellular Localization cell membrane
Tissue Specificity Tonsil
Storage The RTU should be stored at 2~8°C protecting from light (Do not freeze),Valid for 12 months.
Shipping Ice bag
background CD74 is a membrane binding subunit of the class II related invariant chain of the major histocompatibility complex. CD74 is mainly used to label lymphocytes in germinal center and in the mantle cell area of lymph nodes. This does not label plasma cells or thymocytes, but usually labels dendritic cells. About 90% of low-grade B-cell lymphoma and 20% of low-grade T-cell lymphoma are expressing CD74, but in high-grade lymphoma, the ability to distinguish B cells from T cells is decreased.
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