Fetuin B Polyclonal Antibody(Capture/Detector) (AN002500P)
For research use only.
| Verified Samples |
Verified Samples in ELISA: Recombinant Mouse Fetuin B protein, Mouse serum, Mouse plasma Verified Samples in IHC: Human liver |
| Dilution | ELISA Capture 2-8 μg/mL, ELISA Detector 0.1-0.4 μg/mL, IHC 1:300-1:600 |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | ELISA Capture/Detector, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant Mouse Fetuin B protein expressed by Mammalian |
| Abbre | Fetuin B |
| Synonyms | 2310011O17Rik, AI255764, D17980, Gugu, Fetub |
| Swissprot | |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cardiovascular |
| Conjugation | Unconjugated |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
| background | Fetuins are members of the cystatin superfamily of cysteine protease inhibitors. Additional members of this superfamily are kininogen and histidine-rich glycoprotein. Fetuin A and B are two known members of the fetuin family. Hepatocytes are believed to be the principal cellular source, but other cell types also express it. Fetuin A, also known as alpha 2-Heremans-Schmid glycoprotein, is an inhibitor of basic calcium phosphate precipitation and a negative acute-phase protein. Normal circulating levels of Fetuin A in adults (300-600 ug/mL) fall significantly (30-50%) during injury and infection. Fetuin B is a newer member whose function is not fully characterized. Fetuin A and B display similarities and differences in their characteristics. Fetuin B exhibits reduction of calcification, while both mRNA levels were down regulated during the acute phase in inflammation-induced rats. However, they share only 20% amino acid sequence identity. The amounts of Fetuin B in human serum, unlike Fetuin A, vary with gender and are higher in females than in males. |
Other Clones
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Other Formats
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Unconjugated
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