ICAM-1/CD54 Monoclonal Antibody(Capture) (AN001440P)
For research use only.
| Verified Samples | Verified Samples in ELISA: Recombinant Rat ICAM-1/CD54 protein, Rat serum, Rat plasma |
| Dilution | ELISA Capture 2-8 μg/mL |
| Isotype | Mouse IgG1 |
| Host | Mouse |
| Reactivity | Rat |
| Applications | ELISA Capture |
| Clonality | Monoclonal |
| Immunogen | Recombinant Rat ICAM-1/CD54 Protein expressed by Mammalian |
| Abbre | ICAM-1/CD54 |
| Synonyms | InterceLLuLar adhesion moLecuLe 1, ICAM-1, CD54, Icam1, Icam-1 |
| Swissprot | |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
| Purification Method | Protein A/G Purification |
| Clone No. | 2F7 |
| Conjugation | Unconjugated |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
| background | ICAM-1 (intercellular adhesion molecule-1),also known as CD54,is a transmembrane protein that is upregulated on endothelial and epithelial cells at sites of inflammation. It mediates the vascular adhesion and paracellular migration of leukocytes expressing activated lFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). It also binds several non-integrin ligands including CD43/Sialophorin,Fibrinogen,Hyaluronan,rhinoviruses,and Plasmodium falciparum-infected erythrocytes. Soluble ICAM-1 promotes angiogenesis and serves an indicator of vascular endothelial cell activation or damage. Elevated levels of soluble ICAM-1 are associated with cardiovascular disease,type 2 diabetes,organ transplant dysfunction,oxidant stress,increased abdominal fat mass,hypertension,liver disease,certain malignancies,and cerebral malaria. |
Other Clones
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Other Formats
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Unconjugated
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